Megrez PL300B Orthopedic Surgical Robot

Developed by Perlove Medical, the Megrez PL300B is an orthopedic surgical navigation and positioning system that combines optical tracking technology with robotic arm positioning to assist surgeons in minimally invasive spine and trauma procedures. As the first NMPA-approved integrated solution combining an orthopedic surgical robot with 3D C-arm imaging from a single Chinese manufacturer, the system received Class III medical device registration in June 2022.

Product Overview

The Megrez name derives from Delta Ursae Majoris, the fourth star in the Big Dipper constellation, known in Chinese astrology as “Tān Quán” (天權) or the star of wisdom. The system consists of a host computer, robotic arm, surgical planning and control software, optical tracking system, master trolley, and navigation positioning toolkit.

What distinguishes the Megrez PL300B from other orthopedic robots is its native integration with Perlove’s proprietary 3D C-arm. Rather than requiring surgeons to calibrate separate imaging and navigation systems from different manufacturers, the Megrez achieves automatic registration between optical position finder, patient anatomy, and image coordinates through integrated adaptive registration technology.

Key Features

Designed for spine surgery, Perlove’s Megrez PL300B combines an optical tracker and 3D C-arm from a single manufacturer, achieving ~1mm positioning accuracy with automatic multi-system registration.

• Automatic Multi-System Registration: Integrated adaptive technology automatically establishes coordinate associations between the optical tracker, patient, and 3D imaging data without manual calibration steps
• Sub-Millimeter Positioning Accuracy: The optical tracking system and robotic arm achieve positioning precision of approximately 1mm, meeting international standards for spinal instrumentation
• Multiple Screw Path Planning: Surgeons can plan multiple pedicle screw trajectories in a single session, improving procedural efficiency compared to sequential manual positioning
• Reduced Radiation Exposure: Robot-assisted positioning eliminates the need for repeated fluoroscopic verification during nail insertion, significantly reducing radiation dose to surgical staff
• Minimally Invasive Approach: Enables screw placement through 1-2cm incisions rather than traditional open surgical exposure

Technical Specifications

At ~1mm positioning accuracy, the NMPA Class III approved Megrez PL300B uses high-precision optical tracking and automatic registration with Perlove’s proprietary 3D C-arm for spinal instrumentation.

Clinical Applications

The Megrez PL300B supports multiple orthopedic and spine surgery applications:

Spine Surgery: Pedicle screw placement, vertebroplasty, kyphoplasty, and other spinal instrumentation procedures. The system allows surgeons to perform pre-operative planning using 3D image data and precisely target screw entry points during the procedure.

Orthopedic Trauma: Positioning of surgical instruments and implants during fracture fixation procedures. The robotic arm positioning replaces bare-hand positioning, improving stability and accuracy.

Sacral Neuromodulation: The system has been used to assist in sacral nerve stimulator implantation, enabling optimal electrode placement through reduced puncture attempts and shortened procedure duration.

Clinical benefits reported include reduction in surgical time by over 50%, decrease in blood loss by more than 95%, and lower complication rates compared to traditional manual techniques. The standardized workflow also helps less experienced surgeons perform complex procedures more reliably.

Regulatory Status

The Megrez PL300B received NMPA Class III medical device registration on June 14, 2022. Perlove became the first Chinese manufacturer to receive approval for an integrated orthopedic surgical robot and 3D C-arm solution. The company has indicated development of a second-generation orthopedic surgical robot solution for future regulatory submissions.

System Integration

The Megrez PL300B is designed to work as part of Perlove’s spine surgery full-process solution, which combines:

1. 3D C-arm: Provides intraoperative three-dimensional imaging and CT-like tomography
2. Surgical Robot: Offers precision navigation and positioning based on 3D image data
3. Planning Software: Enables pre-operative path planning and real-time navigation

This integrated approach provides what Perlove describes as a “3D image + intelligent navigation” guarantee for minimally invasive orthopedic surgery.

Frequently Asked Questions

What is the positioning accuracy of the Megrez PL300B?

The Megrez PL300B achieves approximately 1mm (sub-millimeter) positioning accuracy through its high-precision optical tracking system and robotic arm, meeting international standards for spinal instrumentation.

Which imaging systems work with the Megrez PL300B?

The Megrez PL300B is designed to integrate with Perlove’s proprietary 3D C-arm system. This native integration enables automatic registration between imaging and navigation systems without the calibration challenges associated with combining equipment from different manufacturers.

What types of spine procedures can the Megrez PL300B assist?

The system supports pedicle screw placement, vertebroplasty, kyphoplasty, and other spinal instrumentation procedures. It has also been used for orthopedic trauma surgery and sacral nerve stimulator implantation.