KF-PRX High-Throughput Digital Pathology Scanner
The KF-PRX series delivers industrial-scale scanning capacity for centralized pathology laboratories and commercial diagnostic services. With configurations supporting 150 to 1,200 slides per load and continuous loading capability, these scanners enable 24/7 unattended operation for high-volume digitization workflows.
Product Overview
KFBIO engineered the KF-PRX line specifically for laboratories processing thousands of slides daily. The platform combines the core imaging technology of the KF-PRO series with enhanced automation features including servo-driven continuous loading, staining rack compatibility, and extended unattended operation modes.
Central laboratories, independent pathology services, and population screening programs represent primary adoption scenarios. The scanner’s throughput characteristics align with requirements for cervical cancer screening initiatives processing hundreds of thousands of samples annually.
Key Features
Designed for high-volume pathology digitization, the KF-PRX series processes approximately 200 slides per hour at 20× with servo-driven continuous loading across 150-, 480-, and 1,200-slide configurations for true 24/7 unattended operation.
Continuous Loading System: Servo-driven mechanism enables slide replenishment without interrupting active scanning, supporting true 24/7 operation
Staining Rack Compatibility: Direct placement of standard laboratory staining racks eliminates manual slide transfer, reducing handling time and potential for labeling errors
Extended Capacity: Models range from 150-slide entry configurations to 1,200-slide maximum capacity for ultra-high-volume operations
Consistent Speed Performance: Maintains 15-second per slide scanning speed (20× magnification) regardless of batch size
Dual Imaging Support: Full brightfield and fluorescence capability across all throughput configurations
Remote Monitoring: Network connectivity enables laboratory managers to track scanning progress and receive completion notifications
Technical Specifications
Designed for central laboratories and population screening, the KF-PRX maintains 15-second per slide throughput at 20× with 50nm positioning accuracy, supporting 24/7 continuous operation across 150- to 1,200-slide model configurations.
| Parameter | Specification |
|---|---|
| Slide Capacity | 150 / 480 / 1,200 slides (model dependent) |
| Loading Mode | Continuous servo loading |
| Scanning Throughput | ~200 slides/hour at 20× |
| Objective Lens Options | 4×, 10×, 20× (NA 0.8), 40× (NA 0.95), 60×, 100× |
| Resolution | 0.25 μm/pixel (20×), 0.125 μm/pixel (40×) |
| Scanning Speed | 15s/slide at 20×, 25s/slide at 40× |
| Positioning Accuracy | 50nm |
| Maximum Magnification | 80× digital |
| Operation Mode | 24/7 continuous |
Model Variants
KF-PRX-S: Entry configuration with 150-slide capacity, designed for medium-volume laboratories seeking automation benefits without maximum throughput requirements.
KF-PRX-M: Mid-range 480-slide capacity variant balancing throughput with equipment footprint. Processes approximately 200 slides per hour at 20× magnification.
KF-PRX-1200: Maximum capacity configuration loading 1,200 slides simultaneously. Supports unlimited 24/7 loading mode with servo-driven continuous replenishment.
Clinical Applications
Central Laboratory Operations: Regional pathology centers consolidating specimen processing from multiple satellite facilities deploy KF-PRX scanners to handle aggregated daily volumes.
Commercial Diagnostics: Independent laboratories offering digital pathology services to hospitals without in-house scanning capability rely on KF-PRX throughput for viable service economics.
Population Screening Programs: Large-scale cervical cancer and other screening initiatives require high-volume digitization for AI-assisted analysis. KFBIO’s screening projects in China and Brazil use KF-PRX scanners feeding into AI diagnostic pipelines.
Biobanking and Archives: Research institutions digitizing historical slide collections for long-term preservation and retrospective studies benefit from the scanner’s batch processing efficiency.
Integration with AI Workflows
The KF-PRX series integrates directly with KFBIO’s AI diagnostic systems:
- Scanned images transfer automatically to AI analysis queues
- Cervical cancer AI system processes cytology slides with 50-70% negative case filtering
- Tuberculosis AI system analyzes sputum smear microscopy slides
- Results return to telepathology platform for pathologist review
This integrated workflow has enabled screening programs to process 100,000+ cases annually with only 2 pathologists, versus 4 pathologists required for manual review under regulatory limits of 100 slides per pathologist per day.
Regulatory Status
| Region | Status | Date |
|---|---|---|
| China (NMPA) | Class II Registered | 2017 |
| Europe (CE) | CE Certified | Yes |
| United States (FDA) | Not Applied | - |
Frequently Asked Questions
What is the maximum slide capacity of the KF-PRX series?
The KF-PRX-1200 model supports 1,200 slides per load with continuous loading capability for unlimited daily throughput during 24/7 operation.
Can the KF-PRX scanner operate continuously?
Yes. The servo-driven continuous loading system allows slide replenishment without stopping active scanning, enabling true 24/7 unattended operation for high-volume laboratories.
How does KF-PRX integrate with laboratory staining workflows?
The scanner accepts standard laboratory staining racks directly, eliminating manual slide transfer from staining equipment. This reduces handling time and minimizes potential labeling errors.
What throughput can laboratories expect from KF-PRX scanners?
At 20× magnification, the KF-PRX series processes approximately 200 slides per hour. Daily capacity depends on operational hours, with 24/7 operation enabling 4,000+ slides per day.
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Sources
Publicly available references used for the data on this page. See data methodology for verification standards.