Angelexo

Angelexo Scientific Inc. develops intelligent rehabilitation robots integrating brain-computer interface technology with exoskeleton systems. Founded in 2017 by Dr. Li Luya, the company achieved a significant milestone in 2022 when its LiteStepper® became the world’s first single lower-limb exoskeleton robot to receive regulatory approval, addressing a critical gap in hemiplegia rehabilitation.

Company Overview

Headquartered in Hangzhou’s Xiaoshan District, Angelexo operates a research-driven organization focused on neurological rehabilitation. The company maintains domestic subsidiaries in Beijing, Zhengzhou (Henan), and Hefei (Anhui), with overseas business development offices in Seattle, USA and Vancouver, Canada.

The founding team combines expertise in robotics, artificial intelligence, biomedical engineering, and clinical medicine. Dr. Li Luya, the founder, brings deep knowledge in translating clinical needs into engineering solutions for rehabilitation applications.

Angelexo was recognized as a National High-tech Enterprise in 2021 and independently undertook the Zhejiang Province Key R&D Program Project. The company was also selected for Hangzhou’s Eagle Plan for high-growth enterprises and received designation as a national and Zhejiang province technology-based SME.

Core Products

LiteStepper® Single Lower-Limb Exoskeleton

LiteStepper® represents the company’s flagship product—the world’s first single lower-limb rehabilitation exoskeleton robot. The device received NMPA Class II medical device registration in September 2022.

Unlike conventional dual-leg exoskeletons that control both limbs through preset programs, LiteStepper® employs intelligent gait learning to capture movement data from the patient’s healthy limb and guide the affected side accordingly. This approach promotes active patient participation and supports neural pathway reconstruction through brain plasticity mechanisms.

Clinical applications include stroke rehabilitation, traumatic brain injury recovery, post-orthopedic surgery rehabilitation, and treatment for muscle atrophy, weakness, and gait abnormalities caused by neurological conditions.

ExoMax® Ankle Rehabilitation Robot

ExoMax® targets ankle joint rehabilitation in adult patients. The device has obtained NMPA registration and supports range-of-motion exercises and muscle strength recovery for patients with ankle dysfunction.

ExoPedia® Pediatric Ankle Rehabilitation Robot

Approved by NMPA as a Class II innovative medical device in June 2023, ExoPedia® addresses the specific physiological and psychological needs of pediatric patients. The device provides immersive treatment experiences to improve muscle strength, balance, coordination, and ankle joint range of motion in children.

Technology & Innovation

Founded in 2017, Angelexo combines non-invasive brain-computer interface sensing with exoskeleton hardware to enable active neural-pathway recovery for hemiplegic and stroke patients.

Angelexo has accumulated over 100 proprietary intellectual property rights, including more than 20 invention patents. The company’s core technology portfolio encompasses:

• Non-invasive Brain-Computer Interface: Enables detection and interpretation of patient motor intent without surgical implantation
• Human-Machine Intelligent Interaction: Facilitates coordinated movement between patient and robotic system
• Autonomous Machine Learning: Allows real-time adaptation to individual patient gait patterns
• Redundant Sensor Fusion: Combines multiple sensor inputs for precise movement tracking
• Bone-Muscle Metabolic Sensing: Non-invasive monitoring of metabolic parameters during rehabilitation
• Biomimetic Exoskeleton Design: Anatomically-aligned mechanical structures for natural movement patterns

The company’s technical approach emphasizes converting passive rehabilitation into active recovery, where patients drive their own rehabilitation through engagement with the healthy limb, promoting neuroplasticity and functional recovery.

Clinical Partnerships

Angelexo has established clinical research collaborations with numerous medical institutions including:

• National Rehabilitation Aids Research Center Affiliated Hospital
• Tongji University Affiliated Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center)
• First Affiliated Hospital of Zhejiang University
• Second Affiliated Hospital of Zhejiang University
• Hangzhou First People’s Hospital
• Fifth Affiliated Hospital of Zhengzhou University

Product Pipeline

Beyond its approved products, Angelexo is developing an expanded rehabilitation robot portfolio including:

• Single and dual ankle-foot rehabilitation robots
• Upper limb rehabilitation robots
• Hand function rehabilitation robots
• Pediatric cerebral palsy rehabilitation robots
• Trunk rehabilitation robots
• Balance training robots

Key Milestones

• 2017: Company founded in Hangzhou
• 2018: Recognized as national technology-based SME
• 2019: Recognized as Zhejiang Province technology-based SME
• 2020: Established Zhengzhou subsidiary; selected for Hangzhou Eagle Plan
• 2021: National High-tech Enterprise certification; undertook Zhejiang Key R&D Program
• 2022: Completed Pre-A financing; LiteStepper® received NMPA approval; established Beijing branch
• 2023: ExoPedia® received NMPA innovative medical device registration; LiteStepper® won Industrial Design Award

Frequently Asked Questions

What products does Angelexo offer?

Angelexo offers three NMPA-approved rehabilitation robots: LiteStepper® for single lower-limb hemiplegia rehabilitation, ExoMax® for adult ankle rehabilitation, and ExoPedia® for pediatric ankle rehabilitation. The company is developing additional products for upper limb, hand function, and trunk rehabilitation.

Is Angelexo publicly traded?

No, Angelexo is a privately held company. The company completed a Pre-A round of financing in April 2022 led by October Capital and Shanghai Xuyuan Investment, raising tens of millions of RMB.

What makes LiteStepper® different from other exoskeletons?

LiteStepper® is the world’s first single lower-limb exoskeleton robot, designed specifically for hemiplegia patients. Unlike dual-leg systems that control both limbs through preset programs, LiteStepper® uses intelligent gait learning to capture the healthy limb’s movement patterns and guide the affected side, promoting active rehabilitation and neural pathway reconstruction.